Getting used to using your keyboard exclusively and leaving your mouse behind will make you much more efficient at performing any task on any Windows system.
Windows key + R = Run menu
This is usually followed by:
cmd = Command Prompt
iexplore + "web address" = Internet Explorer
compmgmt.msc = Computer Management
dhcpmgmt.msc = DHCP Management
dnsmgmt.msc = DNS Management
services.msc = Services
eventvwr = Event Viewer
dsa.msc = Active Directory Users and Computers
dssite.msc = Active Directory Sites and Services
Windows key + E = Explorer
ALT + Tab = Switch between windows
ALT, Space, X = Maximize window
CTRL + Shift + Esc = Task Manager
Windows key + Break = System properties
Windows key + F = Search
Windows key + D = Hide/Display all windows
CTRL + C = copy
CTRL + X = cut
CTRL + V = paste
Also don't forget about the "Right-click" key next to the right Windows key on your keyboard. Using the arrows and that key can get just about anything done once you've opened up any program.
[Alt] and [Esc] Switch between running applications
[Alt] and letter Select menu item by underlined letter
[Ctrl] and [Esc] Open Program Menu
[Ctrl] and [F4] Close active document or group windows (does not work with some applications)
[Alt] and [F4] Quit active application or close current window
[Alt] and [-] Open Control menu for active document
Ctrl] Lft., Rt. arrow Move cursor forward or back one word
Ctrl] Up, Down arrow Move cursor forward or back one paragraph
[F1] Open Help for active application
Windows+M Minimize all open windows
Shift+Windows+M Undo minimize all open windows
Windows+F1 Open Windows Help
Windows+Tab Cycle through the Taskbar buttons
Windows+Break Open the System Properties dialog box
Right SHIFT for eight seconds........ Switch FilterKeys on and off.
Left ALT +left SHIFT +PRINT SCREEN....... Switch High Contrast on and off.
Left ALT +left SHIFT +NUM LOCK....... Switch MouseKeys on and off.
SHIFT....... five times Switch StickyKeys on and off.
NUM LOCK...... for five seconds Switch ToggleKeys on and off.
END....... Display the bottom of the active window.
HOME....... Display the top of the active window.
NUM LOCK+ASTERISK....... on numeric keypad (*) Display all subfolders under the selected folder.
NUM LOCK+PLUS SIGN....... on numeric keypad (+) Display the contents of the selected folder.
NUM LOCK+MINUS SIGN....... on numeric keypad (-) Collapse the selected folder.
LEFT ARROW...... Collapse current selection if it's expanded, or select parent folder.
RIGHT ARROW....... Display current selection if it's collapsed, or select first subfolder.
Type the following commands in your Run Box (Windows Key + R) or Start Run
devmgmt.msc = Device Manager
msinfo32 = System Information
cleanmgr = Disk Cleanup
ntbackup = Backup or Restore Wizard (Windows Backup Utility)
mmc = Microsoft Management Console
excel = Microsoft Excel (If Installed)
msaccess = Microsoft Access (If Installed)
powerpnt = Microsoft PowerPoint (If Installed)
winword = Microsoft Word (If Installed)
frontpg = Microsoft FrontPage (If Installed)
notepad = Notepad
wordpad = WordPad
calc = Calculator
msmsgs = Windows Messenger
mspaint = Microsoft Paint
wmplayer = Windows Media Player
rstrui = System Restore
netscp6 = Netscape 6.x
netscp = Netscape 7.x
netscape = Netscape 4.x
waol = America Online
control = Opens the Control Panel
control printers = Opens the Printers Dialog
File Under : windows